By its cross correlation method (PCCS) NANOPHOX is able to eliminate scattering information that is not due to Brownian motion as e.g. multiple scatter, cuvette surface inhomogeneity etc.. This results in the best possible raw data for evaluation.
In NANOPHOX the user has the choice between 2nd Cumulant, auto-NNLS
(an operator independent evaluation mode for validation tasks) and the expert-NNLS mode (with guided manual fit range seting).